EMDB < Search results

EMBL

was set up in 1974 as Europe’s flagship laboratory for the life sciences – an intergovernmental organisation with more than 80 independent research groups covering the spectrum of molecular biology:

Research:

perform basic research in molecular biology

Services:

offer vital services to scientists in the member states

Training

scientists, students and visitors at all levels

Transfer

and development of technology

Develop

new instruments and methods

Integrating

life science research in Europe

More about EMBL

Six sites

represent EMBL in Europe.

Barcelona

Tissue biology and disease modelling

Grenoble

Structural biology

Hamburg

Structural biology

Heidelberg

Main laboratory

Hinxton

EMBL-EBI: European Bioinformatics Institute

Rome

Epigenetics and neurobiology

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author:"Anders C" AND author_orcid:"0000-0002-7601-210x"

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EMD-5858

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Structures of Cas9 endonucleases reveal RNA-mediated conformational activation

Release date: Feb. 19, 2014
Resolution: 19.0 Å
EM Method: Single-particle

Jinek M, Jiang F, Taylor DW, Sternberg SH, Kaya E, Ma E, Anders C, Hauer M, Zhou K, Lin S, Kaplan M, Iavarone AT, Charpentier E, Nogales E, Doudna JA

Science (2014) 343 pp. 1247997- [ Pubmed: 24505130 DOI: doi:10.1126/science.1247997 ]

Sample:

Crispr-associated endonuclease cas9 (159 kDa, Protein from Streptococcus pyogenes)
Apo-cas9 (160 kDa, Sample)

EMD-5859

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Structures of Cas9 endonucleases reveal RNA-mediated conformational activation

Release date: Feb. 19, 2014
Resolution: 21.0 Å
EM Method: Single-particle

Jinek M, Jiang F, Taylor DW, Sternberg SH, Kaya E, Ma E, Anders C, Hauer M, Zhou K, Lin S, Kaplan M, Iavarone AT, Charpentier E, Nogales E, Doudna JA

Science (2014) 343 pp. 1247997- [ Pubmed: 24505130 DOI: doi:10.1126/science.1247997 ]

Sample:

Cas9 loaded with crrna:tracrrna (196 kDa, Sample)
Crispr rna (14 kDa, RNA from Streptococcus pyogenes)
Crispr-associated endonuclease cas9 (159 kDa, Protein from Streptococcus pyogenes)
Trans-activating crispr rna (24 kDa, RNA from Streptococcus pyogenes)

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EMD-5860

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Structures of Cas9 endonucleases reveal RNA-mediated conformational activation

Release date: Feb. 19, 2014
Resolution: 21.0 Å
EM Method: Single-particle

Jinek M, Jiang F, Taylor DW, Sternberg SH, Kaya E, Ma E, Anders C, Hauer M, Zhou K, Lin S, Kaplan M, Iavarone AT, Charpentier E, Nogales E, Doudna JA

Science (2014) 343 pp. 1247997- [ Pubmed: 24505130 DOI: doi:10.1126/science.1247997 ]

Sample:

Crispr-associated endonuclease cas9 (159 kDa, Protein from Streptococcus pyogenes)
Crispr rna (14 kDa, RNA from Streptococcus pyogenes)
55 bp dna duplex target strand (17 kDa, DNA from Enterobacteria phage lambda)
Trans-activating crispr rna (24 kDa, RNA from Streptococcus pyogenes)
55 bp dna duplex non-target strand (17 kDa, DNA from Enterobacteria phage lambda)
Cas9 loaded with crrna:tracrrna and bound to target dna duplex (230 kDa, Sample)

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Showing 1 - 3 of 3. Page 1 of 1

Display: Statistics

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Select database:

EMDB [3]

Format:

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